Measuring significant changes in chromatin conformation with ACCOST

Chromatin conformation assays such as Hi-C cannot directly measure differences in 3D architecture between cell types or cell states. For this purpose, two or more Hi-C experiments must be carried out, but direct comparison of the resulting Hi-C matrices is confounded by several features of Hi-C data...

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Detalles Bibliográficos
Autores principales: Cook, Kate B, Hristov, Borislav H, Le Roch, Karine G, Vert, Jean Philippe, Noble, William Stafford
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049724/
https://www.ncbi.nlm.nih.gov/pubmed/32034421
http://dx.doi.org/10.1093/nar/gkaa069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049724/
https://www.ncbi.nlm.nih.gov/pubmed/32034421
http://dx.doi.org/10.1093/nar/gkaa069

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