Sequence specificity, energetics and mechanism of mismatch recognition by DNA damage sensing protein Rad4/XPC

The ultraviolet (UV) radiation-induced DNA lesions play a causal role in many prevalent genetic skin-related diseases and cancers. The damage sensing protein Rad4/XPC specifically recognizes and repairs these lesions with high fidelity and safeguards genome integrity. Despite considerable progress,...

Descripción completa

Detalles Bibliográficos
Autores principales: Panigrahi, Abhinandan, Vemuri, Hemanth, Aggarwal, Madhur, Pitta, Kartheek, Krishnan, Marimuthu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049735/
https://www.ncbi.nlm.nih.gov/pubmed/32047903
http://dx.doi.org/10.1093/nar/gkaa078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049735/
https://www.ncbi.nlm.nih.gov/pubmed/32047903
http://dx.doi.org/10.1093/nar/gkaa078

Ejemplares similares