Selective Loss of Responsiveness to Exogenous but Not Endogenous Cyclic-Dinucleotides in Mice Expressing STING-R231H

Stimulator of interferon genes (STING) plays a central role in innate immune responses to viral and intracellular bacterial infections, and cellular damage. STING is a cytosolic sensor of cyclic dinucleotides (CDNs) including those produced by pathogenic bacteria and those arising endogenously as pr...

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Detalles Bibliográficos
Autores principales: Walker, Melissa M., Kim, Soojin, Crisler, William J., Nguyen, Kimberlie, Lenz, Laurel L., Cambier, John C., Getahun, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049784/
https://www.ncbi.nlm.nih.gov/pubmed/32153571
http://dx.doi.org/10.3389/fimmu.2020.00238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049784/
https://www.ncbi.nlm.nih.gov/pubmed/32153571
http://dx.doi.org/10.3389/fimmu.2020.00238

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