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Selective Loss of Responsiveness to Exogenous but Not Endogenous Cyclic-Dinucleotides in Mice Expressing STING-R231H

Stimulator of interferon genes (STING) plays a central role in innate immune responses to viral and intracellular bacterial infections, and cellular damage. STING is a cytosolic sensor of cyclic dinucleotides (CDNs) including those produced by pathogenic bacteria and those arising endogenously as pr...

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Detalles Bibliográficos
Autores principales:	Walker, Melissa M., Kim, Soojin, Crisler, William J., Nguyen, Kimberlie, Lenz, Laurel L., Cambier, John C., Getahun, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049784/ https://www.ncbi.nlm.nih.gov/pubmed/32153571 http://dx.doi.org/10.3389/fimmu.2020.00238

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