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Persistent sodium current blockers can suppress seizures caused by loss of low‐threshold D‐type potassium currents: Predictions from an in silico study of K(v)1 channel disorders
OBJECTIVE: Ion channels belonging to subfamily A of voltage‐gated potassium channels (K(v)1) are highly expressed on axons, where they play a key role in determining resting membrane potential, in shaping action potentials, and in modulating action potential frequency during repetitive neuronal firi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049813/ https://www.ncbi.nlm.nih.gov/pubmed/32140647 http://dx.doi.org/10.1002/epi4.12379 |