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The antiepileptic effect of Gastrodiae Rhizoma through modulating overexpression of mTOR and attenuating astrogliosis in pilocarpine mice model

OBJECTIVE: To investigate the effect of water extract of Gastrodiae Rhizoma (GR) on the development of acquired temporal lobe epilepsy (TLE) and on regulating the expression of the mammalian target of rapamycin (mTOR) and semaphorin 3F (SEMA3F). METHODS: A pilocarpine‐induced status epilepticus (SE)...

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Detalles Bibliográficos
Autores principales: Yip, Ka Lai, Koon, Chi Man, Chen, Zi Yi, Chook, Ping, Leung, Ping Chung, Schachter, Steven, Leung, Wai Hong, Mok, Chung Tong, Leung, Howan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049815/
https://www.ncbi.nlm.nih.gov/pubmed/32140643
http://dx.doi.org/10.1002/epi4.12372