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Concentration Determination of >200 Proteins in Dried Blood Spots for Biomarker Discovery and Validation

The use of protein biomarkers as surrogates for clinical endpoints requires extensive multilevel validation including development of robust and sensitive assays for precise measurement of protein concentration. Multiple reaction monitoring (MRM) is a well-established mass-spectrometric method that c...

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Detalles Bibliográficos
Autores principales: Eshghi, Azad, Pistawka, Adam J., Liu, Jun, Chen, Michael, Sinclair, Nicholas J. T., Hardie, Darryl B., Elliott, Monica, Chen, Lei, Newman, Rachael, Mohammed, Yassene, Borchers, Christoph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050112/
https://www.ncbi.nlm.nih.gov/pubmed/31896676
http://dx.doi.org/10.1074/mcp.TIR119.001820