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Concentration Determination of >200 Proteins in Dried Blood Spots for Biomarker Discovery and Validation
The use of protein biomarkers as surrogates for clinical endpoints requires extensive multilevel validation including development of robust and sensitive assays for precise measurement of protein concentration. Multiple reaction monitoring (MRM) is a well-established mass-spectrometric method that c...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050112/ https://www.ncbi.nlm.nih.gov/pubmed/31896676 http://dx.doi.org/10.1074/mcp.TIR119.001820 |