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Epigenetic regulation of epithelial-mesenchymal transition: focusing on hypoxia and TGF-β signaling
Epithelial-mesenchymal transition (EMT) is an important process triggered during cancer metastasis. Regulation of EMT is mostly initiated by outside signalling, including TGF-β, growth factors, Notch ligand, Wnt, and hypoxia. Many signalling pathways have been delineated to explain the molecular mec...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050137/ https://www.ncbi.nlm.nih.gov/pubmed/32114978 http://dx.doi.org/10.1186/s12929-020-00632-3 |