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Epigenetic regulation of epithelial-mesenchymal transition: focusing on hypoxia and TGF-β signaling

Epithelial-mesenchymal transition (EMT) is an important process triggered during cancer metastasis. Regulation of EMT is mostly initiated by outside signalling, including TGF-β, growth factors, Notch ligand, Wnt, and hypoxia. Many signalling pathways have been delineated to explain the molecular mec...

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Detalles Bibliográficos
Autores principales: Lin, Yueh-Te, Wu, Kou-Juey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050137/
https://www.ncbi.nlm.nih.gov/pubmed/32114978
http://dx.doi.org/10.1186/s12929-020-00632-3