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PCBP2 post‐transcriptionally regulates sortilin expression by binding to a C‐rich element in its 3′ UTR

Post‐transcriptional regulation of cytokine production is crucial to ensure appropriate immune responses. We previously demonstrated that poly‐rC‐binding protein‐1 (PCBP1) can act as a trans‐acting factor to stabilize transcripts encoding sortilin, which mediates cytokine trafficking. Here, we repor...

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Detalles Bibliográficos
Autores principales: Yabe‐Wada, Toshiki, Philpott, Caroline C., Onai, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050257/
https://www.ncbi.nlm.nih.gov/pubmed/31961070
http://dx.doi.org/10.1002/2211-5463.12794