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Roux-en-Y Gastric Bypass Surgery Restores Insulin-Mediated Glucose Partitioning and Mitochondrial Dynamics in Primary Myotubes from Severely Obese Humans

BACKGROUND/OBJECTIVES: Impaired insulin-mediated glucose partitioning is an intrinsic metabolic defect in skeletal muscle from severely obese humans (BMI ≥ 40 kg/m(2)). Roux-en-Y gastric bypass (RYGB) surgery has been shown to improve glucose metabolism in severely obese humans. The purpose of the s...

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Detalles Bibliográficos
Autores principales: Kugler, Benjamin A., Gundersen, Anders E., Li, Junhan, Deng, Wenqian, Eugene, Nancy, Gona, Philimon N., Houmard, Joseph A., Zou, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050434/
https://www.ncbi.nlm.nih.gov/pubmed/31624314
http://dx.doi.org/10.1038/s41366-019-0469-y