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Interplay between compartmentalized NAD(+) synthesis and consumption: a focus on the PARP family

Nicotinamide adenine dinucleotide (NAD(+)) is an essential cofactor for redox enzymes, but also moonlights as a substrate for signaling enzymes. When used as a substrate by signaling enzymes, it is consumed, necessitating the recycling of NAD(+) consumption products (i.e., nicotinamide) via a salvag...

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Detalles Bibliográficos
Autor principal: Cohen, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050480/
https://www.ncbi.nlm.nih.gov/pubmed/32029457
http://dx.doi.org/10.1101/gad.335109.119