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Interplay between compartmentalized NAD(+) synthesis and consumption: a focus on the PARP family
Nicotinamide adenine dinucleotide (NAD(+)) is an essential cofactor for redox enzymes, but also moonlights as a substrate for signaling enzymes. When used as a substrate by signaling enzymes, it is consumed, necessitating the recycling of NAD(+) consumption products (i.e., nicotinamide) via a salvag...
Autor principal: | Cohen, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050480/ https://www.ncbi.nlm.nih.gov/pubmed/32029457 http://dx.doi.org/10.1101/gad.335109.119 |
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