The impact of PARPs and ADP-ribosylation on inflammation and host–pathogen interactions

Poly-adenosine diphosphate-ribose polymerases (PARPs) promote ADP-ribosylation, a highly conserved, fundamental posttranslational modification (PTM). PARP catalytic domains transfer the ADP-ribose moiety from NAD(+) to amino acid residues of target proteins, leading to mono- or poly-ADP-ribosylation...

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Detalles Bibliográficos
Autores principales: Fehr, Anthony R., Singh, Sasha A., Kerr, Catherine M., Mukai, Shin, Higashi, Hideyuki, Aikawa, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Special Section: Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050484/
https://www.ncbi.nlm.nih.gov/pubmed/32029454
http://dx.doi.org/10.1101/gad.334425.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050484/
https://www.ncbi.nlm.nih.gov/pubmed/32029454
http://dx.doi.org/10.1101/gad.334425.119

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