Heterozygous loss of epilepsy gene KCNQ2 alters social, repetitive and exploratory behaviors

KCNQ/K(v)7 channels conduct voltage‐dependent outward potassium currents that potently decrease neuronal excitability. Heterozygous inherited mutations in their principle subunits K(v)7.2/KCNQ2 and K(v)7.3/KCNQ3 cause benign familial neonatal epilepsy whereas patients with de novo heterozygous K(v)7...

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Detalles Bibliográficos
Autores principales: Kim, Eung Chang, Patel, Jaimin, Zhang, Jiaren, Soh, Heun, Rhodes, Justin S., Tzingounis, Anastasios V., Chung, Hee Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050516/
https://www.ncbi.nlm.nih.gov/pubmed/31283873
http://dx.doi.org/10.1111/gbb.12599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050516/
https://www.ncbi.nlm.nih.gov/pubmed/31283873
http://dx.doi.org/10.1111/gbb.12599

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