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Heterozygous loss of epilepsy gene KCNQ2 alters social, repetitive and exploratory behaviors
KCNQ/K(v)7 channels conduct voltage‐dependent outward potassium currents that potently decrease neuronal excitability. Heterozygous inherited mutations in their principle subunits K(v)7.2/KCNQ2 and K(v)7.3/KCNQ3 cause benign familial neonatal epilepsy whereas patients with de novo heterozygous K(v)7...
Autores principales: | Kim, Eung Chang, Patel, Jaimin, Zhang, Jiaren, Soh, Heun, Rhodes, Justin S., Tzingounis, Anastasios V., Chung, Hee Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050516/ https://www.ncbi.nlm.nih.gov/pubmed/31283873 http://dx.doi.org/10.1111/gbb.12599 |
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