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Deep neural networks for interpreting RNA-binding protein target preferences

Deep learning has become a powerful paradigm to analyze the binding sites of regulatory factors including RNA-binding proteins (RBPs), owing to its strength to learn complex features from possibly multiple sources of raw data. However, the interpretability of these models, which is crucial to improv...

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Detalles Bibliográficos
Autores principales: Ghanbari, Mahsa, Ohler, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050519/
https://www.ncbi.nlm.nih.gov/pubmed/31992613
http://dx.doi.org/10.1101/gr.247494.118