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The full-length transcriptome of C. elegans using direct RNA sequencing

Current transcriptome annotations have largely relied on short read lengths intrinsic to the most widely used high-throughput cDNA sequencing technologies. For example, in the annotation of the Caenorhabditis elegans transcriptome, more than half of the transcript isoforms lack full-length support a...

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Detalles Bibliográficos
Autores principales: Roach, Nathan P., Sadowski, Norah, Alessi, Amelia F., Timp, Winston, Taylor, James, Kim, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050520/
https://www.ncbi.nlm.nih.gov/pubmed/32024661
http://dx.doi.org/10.1101/gr.251314.119