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Elimination of infectious HIV DNA by CRISPR–Cas9

Current antiretroviral drugs can efficiently block HIV replication and prevent transmission, but do not target the HIV provirus residing in cells that constitute the viral reservoir. Because drug therapy interruption will cause viral rebound from this reservoir, HIV-infected individuals face lifelon...

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Detalles Bibliográficos
Autores principales: Das, Atze T, Binda, Caroline S, Berkhout, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050564/
https://www.ncbi.nlm.nih.gov/pubmed/31450074
http://dx.doi.org/10.1016/j.coviro.2019.07.001