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Association of EPCR Polymorphism rs867186-GG With Severity of Human Malaria
BACKGROUND: Cerebral malaria (CM) is characterized by the sequestration of Plasmodium-infected erythrocytes (pRBCs) to host brain microvasculature beds via P. falciparum erythrocyte membrane protein 1 (PfEMP1). Under normal conditions, activated protein C (APC) bound to endothelial protein C recepto...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050639/ https://www.ncbi.nlm.nih.gov/pubmed/32153634 http://dx.doi.org/10.3389/fgene.2020.00056 |