Cargando…

Association of EPCR Polymorphism rs867186-GG With Severity of Human Malaria

BACKGROUND: Cerebral malaria (CM) is characterized by the sequestration of Plasmodium-infected erythrocytes (pRBCs) to host brain microvasculature beds via P. falciparum erythrocyte membrane protein 1 (PfEMP1). Under normal conditions, activated protein C (APC) bound to endothelial protein C recepto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cespedes, Juan Carlos, Hibbert, Jacqueline, Krishna, Sri, Yan, Fengxia, Bharti, Praveen K., Stiles, Jonathan K., Liu, Mingli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050639/ https://www.ncbi.nlm.nih.gov/pubmed/32153634 http://dx.doi.org/10.3389/fgene.2020.00056

Ejemplares similares

The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria
por: Shabani, Estela, et al.
Publicado: (2016)

Association of the endothelial protein C receptor (PROCR) rs867186-G allele with protection from severe malaria
por: Naka, Izumi, et al.
Publicado: (2014)

Genetic polymorphisms linked to susceptibility to malaria
por: Driss, Adel, et al.
Publicado: (2011)

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania
por: Hansson, Helle Holm, et al.
Publicado: (2015)

Heme Mediated STAT3 Activation in Severe Malaria
por: Liu, Mingli, et al.
Publicado: (2012)

The EIF2AK4/rs4594236 AG/GG Genotype Is a Hazard Factor of Immunoglobulin Therapy Resistance in Southern Chinese Kawasaki Disease Patients
por: Yu, Hongyan, et al.
Publicado: (2022)

The H3 Haplotype of the EPCR Gene Determines High sEPCR Levels in Critically Ill Septic Patients
por: Vassiliou, Alice G., et al.
Publicado: (2018)

ApoptomiRs of Breast Cancer: Basics to Clinics
por: Sharma, Shivani, et al.
Publicado: (2016)

Evaluation of the Association of Single Nucleotide Polymorphism rs2229238 in Interleukin 6 Receptor Alpha (IL6RA) Gene With the Risk of Preeclampsia
por: Sivaraj, Nagarjuna, et al.
Publicado: (2022)

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria
por: Shabani, Estela, et al.
Publicado: (2017)

Association of Single-Nucleotide Polymorphisms of rs2383206, rs2383207, and rs10757278 With Stroke Risk in the Chinese Population: A Meta-analysis
por: Hu, Xuemei, et al.
Publicado: (2022)

A rare case of quadruple malaria infection from the highly malaria-endemic area of Bastar, Chhattisgarh, India
por: Krishna, Sri, et al.
Publicado: (2017)

The rs2619566, rs10260404, and rs79609816 Polymorphisms Are Associated With Sporadic Amyotrophic Lateral Sclerosis in Individuals of Han Ancestry From Mainland China
por: Zhang, Jie, et al.
Publicado: (2021)

Corrigendum: Association of single-nucleotide polymorphisms of rs2383206, rs2383207, and rs10757278 with stroke risk in the Chinese population: A meta-analysis
por: Hu, Xuemei, et al.
Publicado: (2022)

Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria
por: Lau, Clinton K.Y., et al.
Publicado: (2015)

OPN gene polymorphisms, rs17524488 GG/G, rs11730582 T/C, and rs9138 C/A, and cancer risk in a Chinese population
por: Mi, Yuanyuan, et al.
Publicado: (2015)

Association of soluble endothelial protein C receptor plasma levels and PROCR rs867186 with cardiovascular risk factors and cardiovascular events in coronary artery disease patients: The Athero Gene Study
por: Kallel, Choumous, et al.
Publicado: (2012)

Association of Interleukin-10 Polymorphism (rs1800896, rs1800871, and rs1800872) With Breast Cancer Risk: An Updated Meta-Analysis Based on Different Ethnic Groups
por: Li, Lijun, et al.
Publicado: (2022)

rs401502 and rs11575934 Polymorphisms of the IL-12 Receptor Beta 1 Gene are Protective Against Colorectal Carcinogenesis
por: Jelassi, Refka, et al.
Publicado: (2022)

Association of NLRP3 rs35829419 and rs10754558 Polymorphisms With Risks of Autoimmune Diseases: A Systematic Review and Meta-Analysis
por: Wu, Zubo, et al.
Publicado: (2021)

NCR3 polymorphism, haematological parameters, and severe malaria in Senegalese patients
por: Thiam, Alassane, et al.
Publicado: (2018)

STAT3 Regulates MMP3 in Heme-Induced Endothelial Cell Apoptosis
por: Liu, Mingli, et al.
Publicado: (2013)

ggVennDiagram: An Intuitive, Easy-to-Use, and Highly Customizable R Package to Generate Venn Diagram
por: Gao, Chun-Hui, et al.
Publicado: (2021)

Association between rs7517847 and rs2201841 polymorphisms in IL-23 receptor gene and risk of ankylosing spondylitis: a meta-analysis
por: Xu, Bin, et al.
Publicado: (2015)

Association of mir-196a-2 rs11614913 and mir-149 rs2292832 Polymorphisms With Risk of Cancer: An Updated Meta-Analysis
por: Choupani, Jalal, et al.
Publicado: (2019)

IL1RL1 polymorphisms rs12479210 and rs1420101 are associated with increased lung cancer risk in the Chinese Han population
por: Li, Qi, et al.
Publicado: (2023)

The APC-EPCR-PAR1 axis in sickle cell disease
por: Ramadas, Nirupama, et al.
Publicado: (2023)

The Effects of Endothelial Protein C Receptor Gene Polymorphisms on the Plasma sEPCR Level in Venous Thrombosis Patients
por: Karabıyık, Afife, et al.
Publicado: (2012)

EPCR Gene Ser219Gly Polymorphism and Venous Thromboembolism: A Meta-Analysis of 9,494 Subjects
por: Li, Yan-yan, et al.
Publicado: (2017)

Neuregulin-1 attenuates experimental cerebral malaria (ECM) pathogenesis by regulating ErbB4/AKT/STAT3 signaling
por: Liu, Mingli, et al.
Publicado: (2018)

LINC00673 rs11655237 C>T Polymorphism Impacts Hepatoblastoma Susceptibility in Chinese Children
por: Yang, Tianyou, et al.
Publicado: (2019)

EDNRA Gene rs1878406 Polymorphism is Associated With Susceptibility to Large Artery Atherosclerotic Stroke
por: Wei, Wan, et al.
Publicado: (2022)

CXADR polymorphism rs6517774 modifies islet autoimmunity characteristics and exhibits sex disparity
por: Nygård, Lucas, et al.
Publicado: (2023)

Associations of the miRNA-146a rs2910164 and the miRNA-499a rs3746444 Polymorphisms With Plasma Lipid Levels: A Meta-Analysis
por: Liu, Fuqiang, et al.
Publicado: (2021)

Factor VII, EPCR, aPC Modulators: novel treatment for neuroinflammation
por: Golderman, Valery, et al.
Publicado: (2022)

The Relationship Between rs3212986C>A Polymorphism and Tumor Stage in Lung Cancer Patients
por: Anoushirvani, Ali Arash, et al.
Publicado: (2019)

Genetic Association of ACE2 rs2285666 Polymorphism With COVID-19 Spatial Distribution in India
por: Srivastava, Anshika, et al.
Publicado: (2020)

KLK2 single-nucleotide polymorphism rs198977 is associated with increased susceptibility and hyperleukocytosis in AML
por: Meng, Guangqiang, et al.
Publicado: (2023)

The rs4646 and rs12592697 Polymorphisms in CYP19A1 Are Associated with Disease Progression among Patients with Breast Cancer from Different Racial/Ethnic Backgrounds
por: Armamento-Villareal, Reina, et al.
Publicado: (2016)

ggMOB: Elucidation of genomic conjugative features and associated cargo genes across bacterial genera using genus-genus mobilization networks
por: Nayar, Gowri, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c3l23tvlp8s6eoel9l2n8lsokm