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E6-regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16-positive cervical lesions

Continuous human papillomavirus (HPV) infection is a critical cause of cervical lesions; however, the specific mechanism is currently not clear. E6 is one of the most important oncoproteins associated with HPV, which regulates synthases in the production of prostaglandin E2 (PGE(2)). Notably, PGE(2)...

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Detalles Bibliográficos
Autores principales: Huang, Jie, Diao, Ge, Zhang, Qiong, Chen, Yajie, Han, Jian, Guo, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050979/
https://www.ncbi.nlm.nih.gov/pubmed/32319556
http://dx.doi.org/10.3892/ijo.2020.4983