Cargando…
Functions of Conserved Domains of Human Polynucleotide Phosphorylase on RNA Oxidation
Human polynucleotide phosphorylase (hPNPase), an exoribonuclease that is primarily localized in mitochondria, plays an important role in reducing oxidized RNA and protecting cells under oxidative stress conditions. hPNPase contains two catalytic domains (RPH1 and RPH2) and two RNA binding domains (K...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051052/ https://www.ncbi.nlm.nih.gov/pubmed/32123871 http://dx.doi.org/10.36959/584/448 |