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Emerging role of Fatty acid synthase in tumor initiation: implications for cancer prevention

Targeting metabolic reprogramming has emerged as a promising strategy for therapeutic intervention in cancer. We identify that fatty acid synthase (FASN) is essential for cancer initiation playing a critical role in acquiring three-dimensional (3D) growth properties during transformation. In vivo in...

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Detalles Bibliográficos
Autores principales: Bueno, Maria J., Quintela-Fandino, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051128/
https://www.ncbi.nlm.nih.gov/pubmed/32158923
http://dx.doi.org/10.1080/23723556.2019.1709389