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Targeting MYC through WDR5

The oncoprotein transcription factor MYC is overexpressed in most cancers and is responsible for hundreds of thousands of cancer deaths worldwide every year. MYC is also a highly validated – but currently undruggable – anti-cancer target. We recently showed that breaking the interaction of MYC with...

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Detalles Bibliográficos
Autores principales: Thomas, Lance R., Adams, Clare M., Fesik, Stephen W., Eischen, Christine M., Tansey, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051159/
https://www.ncbi.nlm.nih.gov/pubmed/32158922
http://dx.doi.org/10.1080/23723556.2019.1709388