Lactate dehydrogenase: a marker of diminished antitumor immunity

Lactate dehydrogenase (LDH) levels are inversely related with response to checkpoint inhibitors. Elevated LDH levels are the product of enhanced glycolytic activity of the tumor and tumor necrosis due to hypoxia, the latter being associated with high tumor burden. In this review, we elucidate the ef...

Descripción completa

Detalles Bibliográficos
Autores principales: Van Wilpe, Sandra, Koornstra, Rutger, Den Brok, Martijn, De Groot, Jan Willem, Blank, Christian, De Vries, Jolanda, Gerritsen, Winald, Mehra, Niven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051189/
https://www.ncbi.nlm.nih.gov/pubmed/32158624
http://dx.doi.org/10.1080/2162402X.2020.1731942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051189/
https://www.ncbi.nlm.nih.gov/pubmed/32158624
http://dx.doi.org/10.1080/2162402X.2020.1731942

Ejemplares similares