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Wearing-off at the end of natalizumab dosing intervals is associated with low receptor occupancy

OBJECTIVE: We aimed to investigate whether wearing-off symptoms at the end of the natalizumab dosing interval were associated with clinical and demographic patient characteristics or natalizumab receptor occupancy (RO) on leukocytes. METHODS: In this cross-sectional study of 40 patients with relapsi...

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Detalles Bibliográficos
Autores principales: Bringeland, Gerd Haga, Blaser, Nello, Myhr, Kjell-Morten, Vedeler, Christian Alexander, Gavasso, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051203/
https://www.ncbi.nlm.nih.gov/pubmed/32019768
http://dx.doi.org/10.1212/NXI.0000000000000678