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Variability in protein cargo detection in technical and biological replicates of exosome-enriched extracellular vesicles

Exosomes are extracellular vesicles (EVs) of ~20–200 nm diameter that shuttle DNAs, RNAs, proteins and other biomolecules between cells. The large number of biomolecules present in exosomes demands the frequent use of high-throughput analysis. This, in turn, requires technical replicates (TRs), and...

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Detalles Bibliográficos
Autores principales: Tiruvayipati, Suma, Wolfgeher, Don, Yue, Ming, Duan, FangFang, Andrade, Jorge, Jiang, Hui, Schuger, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051218/
https://www.ncbi.nlm.nih.gov/pubmed/32119684
http://dx.doi.org/10.1371/journal.pone.0228871