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A Peptide-Functionalized Magnetic Nanoplatform-Loaded Melatonin for Targeted Amelioration of Fibrosis in Pressure Overload-Induced Cardiac Hypertrophy

INTRODUCTION: Currently, the unsatisfactory treatment of cardiac hypertrophy is due to the unbridled myocardial fibrosis. Melatonin has been demonstrated to ameliorate cardiac hypertrophy and its accompanied fibrosis in previous studies. But it is not clinically appealing due to its short-lasting ti...

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Detalles Bibliográficos
Autores principales: Zhao, Xueli, Wang, Xuanying, Wang, Jing, Yuan, Jiani, Zhang, Juan, Zhu, Xiaoli, Lei, Changhui, Yang, Qianli, Wang, Bo, Cao, Feng, Liu, Liwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051809/
https://www.ncbi.nlm.nih.gov/pubmed/32161461
http://dx.doi.org/10.2147/IJN.S235518