Enhanced protection conferred by mucosal BCG vaccination associates with presence of antigen-specific lung tissue-resident PD-1(+) KLRG1(−) CD4(+) T cells

BCG, the only vaccine licensed against tuberculosis, demonstrates variable efficacy in humans. Recent preclinical studies highlight the potential for mucosal BCG vaccination to improve protection. Lung tissue-resident memory T cells reside within the parenchyma, potentially playing an important role...

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Detalles Bibliográficos
Autores principales: Bull, N. C., Stylianou, E., Kaveh, D. A., Pinpathomrat, N., Pasricha, J., Harrington-Kandt, R., Garcia-Pelayo, M. C., Hogarth, P. J., McShane, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051908/
https://www.ncbi.nlm.nih.gov/pubmed/30446726
http://dx.doi.org/10.1038/s41385-018-0109-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051908/
https://www.ncbi.nlm.nih.gov/pubmed/30446726
http://dx.doi.org/10.1038/s41385-018-0109-1

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