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Batf2 differentially regulates tissue immunopathology in Type 1 and Type 2 diseases

Basic leucine zipper transcription factor 2 (Batf2) activation is detrimental in Type 1-controlled infectious diseases, demonstrated during infection with Mycobacterium tuberculosis (Mtb) and Listeria monocytogenes Lm. In Batf2-deficient mice (Batf2(−/−)), infected with Mtb or Lm, mice survived and...

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Detalles Bibliográficos
Autores principales: Guler, Reto, Mpotje, Thabo, Ozturk, Mumin, Nono, Justin K., Parihar, Suraj P., Chia, Julius Ebua, Abdel Aziz, Nada, Hlaka, Lerato, Kumar, Santosh, Roy, Sugata, Penn-Nicholson, Adam, Hanekom, Willem A., Zak, Daniel E., Scriba, Thomas J., Suzuki, Harukazu, Brombacher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051910/
https://www.ncbi.nlm.nih.gov/pubmed/30542107
http://dx.doi.org/10.1038/s41385-018-0108-2