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Behavior of 1-Deoxy-, 3-Deoxy- and N-Methyl-Ceramides in Skin Barrier Lipid Models

Ceramides (Cer) are essential components of the skin permeability barrier. To probe the role of Cer polar head groups involved in the interfacial hydrogen bonding, the N-lignoceroyl sphingosine polar head was modified by removing the hydroxyls in C-1 (1-deoxy-Cer) or C-3 positions (3-deoxy-Cer) and...

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Detalles Bibliográficos
Autores principales: Kováčik, Andrej, Pullmannová, Petra, Pavlíková, Ludmila, Maixner, Jaroslav, Vávrová, Kateřina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051948/
https://www.ncbi.nlm.nih.gov/pubmed/32123227
http://dx.doi.org/10.1038/s41598-020-60754-4