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Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model

The development and physiologic role of small intestine (SI) vasculature is poorly studied. This is partly due to a lack of targetable, organ-specific markers for in vivo studies of two critical tissue components: endothelium and stroma. This challenge is exacerbated by limitations of traditional ce...

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Detalles Bibliográficos
Autores principales: Seiler, Kristen M., Bajinting, Adam, Alvarado, David M., Traore, Mahama A., Binkley, Michael M., Goo, William H., Lanik, Wyatt E., Ou, Jocelyn, Ismail, Usama, Iticovici, Micah, King, Cristi R., VanDussen, Kelli L., Swietlicki, Elzbieta A., Gazit, Vered, Guo, Jun, Luke, Cliff J., Stappenbeck, Thaddeus, Ciorba, Matthew A., George, Steven C., Meacham, J. Mark, Rubin, Deborah C., Good, Misty, Warner, Brad W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051952/
https://www.ncbi.nlm.nih.gov/pubmed/32123209
http://dx.doi.org/10.1038/s41598-020-60672-5