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Tumor necrosis factor alpha mediates neuromuscular synapse elimination

During the development of mammalian neuromuscular junction (NMJ), the original supernumerary axon inputs are gradually eliminated, finally leaving each muscle fiber innervated by a single axon terminal. However, the molecular cues that mediate the elimination of redundant axon inputs remain unclear....

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Detalles Bibliográficos
Autores principales: Fu, Xiu-Qing, Peng, Jian, Wang, Ai-Hua, Luo, Zhen-Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051980/
https://www.ncbi.nlm.nih.gov/pubmed/32140252
http://dx.doi.org/10.1038/s41421-020-0143-5