Design, synthesis, and biological evaluation of a multifunctional neuropeptide-Y conjugate for selective nuclear delivery of radiolanthanides

BACKGROUND: Targeting G protein-coupled receptors on the surface of cancer cells with peptide ligands is a promising concept for the selective tumor delivery of therapeutically active cargos, including radiometals for targeted radionuclide therapy (TRT). Recently, the radiolanthanide terbium-161 ((1...

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Detalles Bibliográficos
Autores principales: Chastel, Adrien, Worm, Dennis J., Alves, Isabel D., Vimont, Delphine, Petrel, Melina, Fernandez, Samantha, Garrigue, Philippe, Fernandez, Philippe, Hindié, Elif, Beck-Sickinger, Annette G., Morgat, Clément
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052099/
https://www.ncbi.nlm.nih.gov/pubmed/32124111
http://dx.doi.org/10.1186/s13550-020-0612-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052099/
https://www.ncbi.nlm.nih.gov/pubmed/32124111
http://dx.doi.org/10.1186/s13550-020-0612-8

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