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Tumor-educated B cells promote renal cancer metastasis via inducing the IL-1β/HIF-2α/Notch1 signals

While B cells in the tumor microenvironment (TME) might play important roles in cancer progression, their impacts on the renal cell carcinoma (RCC) metastasis remained unclear, which drew our attention to further explore. We found that RCC tissues could recruit more B cells than the surrounding norm...

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Detalles Bibliográficos
Autores principales: Li, Saiyang, Huang, Chi, Hu, Guanghui, Ma, Junjie, Chen, Yonghui, Zhang, Jin, Huang, Yiran, Zheng, Junhua, Xue, Wei, Xu, Yunfei, Zhai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052134/
https://www.ncbi.nlm.nih.gov/pubmed/32123166
http://dx.doi.org/10.1038/s41419-020-2355-x