A dynamic perfusion based blood-brain barrier model for cytotoxicity testing and drug permeation

The blood-brain barrier (BBB) serves to protect and regulate the CNS microenvironment. The development of an in-vitro mimic of the BBB requires recapitulating the correct phenotype of the in-vivo BBB, particularly for drug permeation studies. However the majority of widely used BBB models demonstrat...

Descripción completa

Detalles Bibliográficos
Autores principales: Elbakary, Basma, Badhan, Raj K. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052153/
https://www.ncbi.nlm.nih.gov/pubmed/32123236
http://dx.doi.org/10.1038/s41598-020-60689-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052153/
https://www.ncbi.nlm.nih.gov/pubmed/32123236
http://dx.doi.org/10.1038/s41598-020-60689-w

Ejemplares similares