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A dynamic perfusion based blood-brain barrier model for cytotoxicity testing and drug permeation
The blood-brain barrier (BBB) serves to protect and regulate the CNS microenvironment. The development of an in-vitro mimic of the BBB requires recapitulating the correct phenotype of the in-vivo BBB, particularly for drug permeation studies. However the majority of widely used BBB models demonstrat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052153/ https://www.ncbi.nlm.nih.gov/pubmed/32123236 http://dx.doi.org/10.1038/s41598-020-60689-w |