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The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection
Epigenetic modifications to histones dictate the differentiation of naïve CD4(+) T cells into different subsets of effector T helper (T(H)) cells. The histone methyltransferase enhancer of zeste homolog 2 (EZH2) has been implicated in the mechanism regulating the differentiation of T(H)1, T(H)2 and...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052164/ https://www.ncbi.nlm.nih.gov/pubmed/30842630 http://dx.doi.org/10.1038/s41423-019-0219-z |