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The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection

Epigenetic modifications to histones dictate the differentiation of naïve CD4(+) T cells into different subsets of effector T helper (T(H)) cells. The histone methyltransferase enhancer of zeste homolog 2 (EZH2) has been implicated in the mechanism regulating the differentiation of T(H)1, T(H)2 and...

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Detalles Bibliográficos
Autores principales: Chen, Xiangyu, Cao, Guoshuai, Wu, Jialin, Wang, Xinxin, Pan, Zhiwei, Gao, Jianbao, Tian, Qin, Xu, Lifan, Li, Zhirong, Hao, Yaxing, Huang, Qizhao, Wang, Pengcheng, Xiao, Minglu, Xie, Luoyingzi, Tang, Shupei, Liu, Zhenyu, Hu, Li, Tang, Jianfang, He, Ran, Wang, Li, Zhou, Xinyuan, Wu, Yuzhang, Chen, Mengjie, Sun, Beicheng, Zhu, Bo, Huang, Jun, Ye, Lilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052164/
https://www.ncbi.nlm.nih.gov/pubmed/30842630
http://dx.doi.org/10.1038/s41423-019-0219-z