A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

Neurofibrillary tangles are a pathological hallmark of Alzheimer’s disease, and their levels correlate with the severity of cognitive dysfunction in humans. However, experimental evidence suggests that soluble tau species cause cognitive deficits and memory impairment. Our recent study suggests that...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Peng, Smith, Benjamin R., Montonye, Michelle L., Kemper, Lisa J., Leinonen-Wright, Kailee, Nelson, Kathryn M., Higgins, LeeAnn, Guerrero, Candace R., Markowski, Todd W., Zhao, Xiaohui, Petersen, Ashley J., Knopman, David S., Petersen, Ronald C., Ashe, Karen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052165/
https://www.ncbi.nlm.nih.gov/pubmed/32123248
http://dx.doi.org/10.1038/s41598-020-60777-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052165/
https://www.ncbi.nlm.nih.gov/pubmed/32123248
http://dx.doi.org/10.1038/s41598-020-60777-x

Ejemplares similares