Nanobody-enabled monitoring of kappa opioid receptor states

Recent studies show that GPCRs rapidly interconvert between multiple states although our ability to interrogate, monitor and visualize them is limited by a relative lack of suitable tools. We previously reported two nanobodies (Nb39 and Nb6) that stabilize distinct ligand- and efficacy-delimited con...

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Detalles Bibliográficos
Autores principales: Che, Tao, English, Justin, Krumm, Brian E., Kim, Kuglae, Pardon, Els, Olsen, Reid H. J., Wang, Sheng, Zhang, Shicheng, Diberto, Jeffrey F., Sciaky, Noah, Carroll, F. Ivy, Steyaert, Jan, Wacker, Daniel, Roth, Bryan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052193/
https://www.ncbi.nlm.nih.gov/pubmed/32123179
http://dx.doi.org/10.1038/s41467-020-14889-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052193/
https://www.ncbi.nlm.nih.gov/pubmed/32123179
http://dx.doi.org/10.1038/s41467-020-14889-7

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