Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer

BACKGROUND: Metabolic alterations can serve as targets for diagnosis and cancer therapy. Due to the highly complex regulation of cellular metabolism, definite identification of metabolic pathway alterations remains challenging and requires sophisticated experimentation. METHODS: We applied a compreh...

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Detalles Bibliográficos
Autores principales: Berndt, Nikolaus, Egners, Antje, Mastrobuoni, Guido, Vvedenskaya, Olga, Fragoulis, Athanassios, Dugourd, Aurélien, Bulik, Sascha, Pietzke, Matthias, Bielow, Chris, van Gassel, Rob, Damink, Steven W. Olde, Erdem, Merve, Saez-Rodriguez, Julio, Holzhütter, Hermann-Georg, Kempa, Stefan, Cramer, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052204/
https://www.ncbi.nlm.nih.gov/pubmed/31819186
http://dx.doi.org/10.1038/s41416-019-0659-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052204/
https://www.ncbi.nlm.nih.gov/pubmed/31819186
http://dx.doi.org/10.1038/s41416-019-0659-3

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