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High-mobility group AT-hook 1 promotes cardiac dysfunction in diabetic cardiomyopathy via autophagy inhibition

High-mobility group AT-hook1 (HMGA1, formerly HMG-I/Y), an architectural transcription factor, participates in a number of biological processes. However, its effect on cardiac remodeling (refer to cardiac inflammation, apoptosis and dysfunction) in diabetic cardiomyopathy remains largely indistinct....

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Detalles Bibliográficos
Autores principales: Wu, Qing-Qing, Liu, Chen, Cai, Zhulan, Xie, Qingwen, Hu, Tongtong, Duan, Mingxia, Wu, Haiming, Yuan, Yuan, Tang, Qizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052237/
https://www.ncbi.nlm.nih.gov/pubmed/32123163
http://dx.doi.org/10.1038/s41419-020-2316-4