Novel elvitegravir nanoformulation for drug delivery across the blood-brain barrier to achieve HIV-1 suppression in the CNS macrophages

The use of antiretroviral therapy (ART) has remarkably decreased the morbidity associated with HIV-1 infection, however, the prevalence of HIV-1-associated neurocognitive disorders (HAND) is still increasing. The blood-brain barrier (BBB) is the major impediment for penetration of antiretroviral dru...

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Detalles Bibliográficos
Autores principales: Gong, Yuqing, Chowdhury, Pallabita, Nagesh, Prashanth K. B., Rahman, Mohammad A., Zhi, Kaining, Yallapu, Murali M., Kumar, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052245/
https://www.ncbi.nlm.nih.gov/pubmed/32123217
http://dx.doi.org/10.1038/s41598-020-60684-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052245/
https://www.ncbi.nlm.nih.gov/pubmed/32123217
http://dx.doi.org/10.1038/s41598-020-60684-1

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