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New aspects of amino acid metabolism in cancer

An abundant supply of amino acids is important for cancers to sustain their proliferative drive. Alongside their direct role as substrates for protein synthesis, they can have roles in energy generation, driving the synthesis of nucleosides and maintenance of cellular redox homoeostasis. As cancer c...

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Detalles Bibliográficos
Autores principales: Vettore, Lisa, Westbrook, Rebecca L., Tennant, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052246/
https://www.ncbi.nlm.nih.gov/pubmed/31819187
http://dx.doi.org/10.1038/s41416-019-0620-5