Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury

Mannose-binding lectin (MBL), an initiator of the lectin pathway (LP) of complement activation, is detrimental in ischemic stroke, as shown in clinical studies and rodent models. Whereas humans have one functional MBL protein, rodents have two isoforms, MBL-A and MBL-C, whose functions relative to t...

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Detalles Bibliográficos
Autores principales: Neglia, Laura, Oggioni, Marco, Mercurio, Domenico, De Simoni, Maria-Grazia, Fumagalli, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052250/
https://www.ncbi.nlm.nih.gov/pubmed/30967639
http://dx.doi.org/10.1038/s41423-019-0225-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052250/
https://www.ncbi.nlm.nih.gov/pubmed/30967639
http://dx.doi.org/10.1038/s41423-019-0225-1

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