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Attenuation of the Hepatoprotective Effects of Ileal Apical Sodium Dependent Bile Acid Transporter (ASBT) Inhibition in Choline-Deficient L-Amino Acid-Defined (CDAA) Diet-Fed Mice

Non-alcoholic fatty liver disease (NAFLD) is a major growing worldwide health problem. We previously reported that interruption of the enterohepatic circulation of bile acids using a non-absorbable apical sodium-dependent bile acid transporter inhibitor (ASBTi; SC-435) reduced the development of NAF...

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Detalles Bibliográficos
Autores principales: Rao, Anuradha, van de Peppel, Ivo P., Gumber, Sanjeev, Karpen, Saul J., Dawson, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052288/
https://www.ncbi.nlm.nih.gov/pubmed/32158763
http://dx.doi.org/10.3389/fmed.2020.00060