Cargando…

Attenuation of the Hepatoprotective Effects of Ileal Apical Sodium Dependent Bile Acid Transporter (ASBT) Inhibition in Choline-Deficient L-Amino Acid-Defined (CDAA) Diet-Fed Mice

Non-alcoholic fatty liver disease (NAFLD) is a major growing worldwide health problem. We previously reported that interruption of the enterohepatic circulation of bile acids using a non-absorbable apical sodium-dependent bile acid transporter inhibitor (ASBTi; SC-435) reduced the development of NAF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rao, Anuradha, van de Peppel, Ivo P., Gumber, Sanjeev, Karpen, Saul J., Dawson, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052288/ https://www.ncbi.nlm.nih.gov/pubmed/32158763 http://dx.doi.org/10.3389/fmed.2020.00060

Ejemplares similares

The Beneficial Effects of Apical Sodium‐Dependent Bile Acid Transporter Inactivation Depend on Dietary Fat Composition
por: van de Peppel, Ivo P., et al.
Publicado: (2020)

Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT
por: Hu, Nien-Jen, et al.
Publicado: (2011)

Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury
por: Truong, Jennifer K., et al.
Publicado: (2022)

Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2)
por: Lionarons, Daniël A., et al.
Publicado: (2012)

Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives
por: Arab, Juan P., et al.
Publicado: (2016)

Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice
por: Truong, Jennifer K., et al.
Publicado: (2023)

Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid–Induced Injury
por: Ferrebee, Courtney B., et al.
Publicado: (2018)

Bile Acid Conjugation on Solid Nanoparticles Enhances ASBT‐Mediated Endocytosis and Chylomicron Pathway but Weakens the Transcytosis by Inducing Transport Flow in a Cellular Negative Feedback Loop
por: Deng, Feiyang, et al.
Publicado: (2022)

Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis
por: Ovadia, Caroline, et al.
Publicado: (2019)

The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
por: Jackson-Litteken, Clay D., et al.
Publicado: (2021)

Ileal mucosal bile acid absorption is increased in Cftr knockout mice
por: Stelzner, Matthias, et al.
Publicado: (2001)

Associations between Ileal Juice Bile Acids and Colorectal Advanced Adenoma
por: Luu, Hung N., et al.
Publicado: (2023)

NPC1L1 Deficiency Suppresses Ileal Fibroblast Growth Factor 15 Expression and Increases Bile Acid Pool Size in High-Fat-Diet-Fed Mice
por: Jia, Lin, et al.
Publicado: (2021)

Determination of basal ileal endogenous losses and standardized ileal digestibility of amino acids in barley fed to growing pigs
por: Spindler, Hanna Katharina, et al.
Publicado: (2016)

Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice
por: Kunst, Roni F., et al.
Publicado: (2022)

Ileal Bile Acid Transporter Inhibition for the Treatment of Chronic Constipation, Cholestatic Pruritus, and NASH
por: Al-Dury, Samer, et al.
Publicado: (2018)

Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation
por: Horváth, Gergő, et al.
Publicado: (2019)

Relationship between the gut microbiota and bile acid composition in the ileal mucosa of Crohn’s disease
por: Bamba, Shigeki, et al.
Publicado: (2022)

Ileal Digestibility of Amino Acids in Meat Meal and Soybean Meal Fed to Growing Pigs
por: Kong, C., et al.
Publicado: (2014)

Effect of keratinase on ileal amino acid digestibility in five feedstuffs fed to growing pigs
por: Huang, Chengfei, et al.
Publicado: (2018)

Bile Acid Composition and Bile Volume in Butter Yellow Fed Rats in Relation to Liver Cancer
por: Mirvish, S., et al.
Publicado: (1960)

Combined ASBT Inhibitor and FGF15 Treatment Improves Therapeutic Efficacy in Experimental Nonalcoholic Steatohepatitis
por: Matye, David J., et al.
Publicado: (2021)

Synergistic Effects of Limosilactobacillus fermentum ASBT-2 with Oxyresveratrol Isolated from Coconut Shell Waste
por: Prakash, Vidhya, et al.
Publicado: (2021)

Substrate Specificities and Inhibition Pattern of the Solute Carrier Family 10 Members NTCP, ASBT and SOAT
por: Grosser, Gary, et al.
Publicado: (2021)

Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor
por: Neumann, Piotr, et al.
Publicado: (2023)

Standardized ileal digestibility of amino acids in soybean meal fed to non-pregnant and pregnant sows
por: Wang, Ke, et al.
Publicado: (2023)

Deficiency in Galectin-3 Promotes Hepatic Injury in CDAA Diet-Induced Nonalcoholic Fatty Liver Disease
por: Nomoto, Kazuhiro, et al.
Publicado: (2012)

Intracellular Concentrations of Borrelia burgdorferi Cyclic Di-AMP Are Not Changed by Altered Expression of the CdaA Synthase
por: Savage, Christina R., et al.
Publicado: (2015)

Changes in Lipidomics, Metabolomics, and the Gut Microbiota in CDAA-Induced NAFLD Mice after Polyene Phosphatidylcholine Treatment
por: Zhang, Jiayuan, et al.
Publicado: (2023)

Elevated bile acids are associated with left ventricular structural changes in biliary atresia
por: Virk, Manpreet K., et al.
Publicado: (2023)

OSTα-OSTβ Guards the Ileal Enterocyte From the Accumulation of Toxic Levels of Bile Acids
por: Boyer, James L.
Publicado: (2018)

Multiple Timescale Dynamic Analysis of Functionally-Impairing Mutations in Human Ileal Bile Acid-Binding Protein
por: Horváth, Gergő, et al.
Publicado: (2022)

Dihydromyricetin ameliorated nonalcoholic steatohepatitis in mice by regulating the composition of serous lipids, bile acids and ileal microflora
por: Miao, Xiaolei, et al.
Publicado: (2023)

Ileal Amino Acid Digestibility of Broken Rice Fed to Postweaned Piglets with or without Multicarbohydrase and Phytase Supplementation
por: Dadalt, J. C., et al.
Publicado: (2016)

Hepatic Liposis and Myocardial Damage in Mice Fed Choline-Deficient or Choline-Supplemented Diets
por: Williams, W. Lane
Publicado: (1960)

Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM
por: Pathania, Monisha, et al.
Publicado: (2021)

Is Bile Acid Malabsorption Really a Common Feature of Crohn's Disease or is It Simply a Consequence of Ileal Resection?
por: Kunstár, Éva, et al.
Publicado: (2011)

Fecal bile acid excretion and messenger RNA expression levels of ileal transporters in high risk gallstone patients
por: Herrera, Jorge, et al.
Publicado: (2009)

Mechanistic insights into the detection of free fatty and bile acids by ileal glucagon-like peptide-1 secreting cells
por: Goldspink, Deborah A., et al.
Publicado: (2017)

PMON295 Investigating the ileal FXR/SHP axis in regulating lipid absorption and enterohepatic recirculation of bile acids
por: Nguyen, James, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_df3shilluph1nb1b9i2k40qpmt