CD47 Deficiency in Mice Exacerbates Chronic Fatty Diet-Induced Steatohepatitis Through Its Role in Regulating Hepatic Inflammation and Lipid Metabolism

Inflammation is one of the hallmarks of non-alcoholic steatohepatitis. CD47 is a widely expressed transmembrane protein that signals through inhibitory receptor signal regulatory protein α (SIRPα) to inhibit macrophage activation and phagocytosis. In this study, we sought to investigate the role of...

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Detalles Bibliográficos
Autores principales: Tao, Hui-Chao, Chen, Ke-Xin, Wang, Xue, Chen, Bo, Zhao, Wai-Ou, Zheng, Yang, Yang, Yong-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052326/
https://www.ncbi.nlm.nih.gov/pubmed/32158445
http://dx.doi.org/10.3389/fimmu.2020.00148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052326/
https://www.ncbi.nlm.nih.gov/pubmed/32158445
http://dx.doi.org/10.3389/fimmu.2020.00148

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