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Assessing accuracy of Weibull shape parameter estimate from historical studies for subsequent sample size calculation in clinical trials with time-to-event outcome

BACKGROUND: Recent developments in literature on sample size calculations for time-to-event outcomes involve assumption of Weibull distributed times. These methods require a point estimate of the Weibull shape parameter obtained from historical studies. However, very limited guidance exists in publi...

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Detalles Bibliográficos
Autores principales: Phadnis, Milind A., Sharma, Palash, Thewarapperuma, Nadeesha, Chalise, Prabhakar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052506/
https://www.ncbi.nlm.nih.gov/pubmed/32154431
http://dx.doi.org/10.1016/j.conctc.2020.100548